BIOCHEMISTRY AND GENETICS INSTITUTE
BIOCHEMISTRY AND GENETICS INSTITUTE, a stand-alone structural unit of the Ufa Federal Research Centre, of the Russian Academy of Sciences (UFRC RAS). Located in Ufa. Established in 1962. Main activities: human molecular and population genetics; organisation and expression of plant and microorganism genes; physiology and biochemistry of plants and animals; biotechnology. The scientists of the Institute have discovered molecular mechanisms of hybrid vigour in agricultural plants, found molecular and genetic causes of differential expression of ribosomal RNA genes in genomes of interspecific plant hybrids; developed a method for iden tification and certification of strains of microorganisms through assigning unique genetic bar codes (to them) based on DNA polymorphism; identified regularities of phytohormone balance changes in case of fungal pathogenesis, deficit of moisture and salination; provided the molecular ethno genetic characteristic of people living in the Volga-Ural region, Central Asia and Caucuses; developed a principal pattern of pre-natal and pre-symptomatic DNA diagnostics of 15 monogenic hereditary human diseases and 10 multifactorial diseases; carried out studies of genetic, biochemical and ecological-specific features of the Bashkir bee, molecular and genetic analysis of ageing and longevity processes, etc. The Institute has created and transferred to breeding organisations of the RB and RF a substantial number of potential lines of durum and soft spring wheat and buck wheat. More than 300 nucleic acid sequences of genes and different fragments of DNA of bacteria, viruses, plants and animals. More than 60 invention patents have been obtained.
